Paul Sperduto AB’80, MD’84, MPP’84, HS’85-‘87, P’16

Wayzata, MN

Paul W. Sperduto is a practicing board-certified radiation oncologist, Fellow of the American Society for Radiation Oncology (FASTRO), author of more than 60 peer-reviewed publications and co-editor of a leading textbook in the field.  Paul has a special interest in brain tumors: he has been Principal Investigator (PI) of three international research studies on the treatment of brain tumors; was recently funded by Merck for another brain tumor clinical trial investigating immunotherapy and radiation and has been co-PI on multiple other trials.

Paul is a senior partner of Minneapolis Radiation Oncology, one of the largest radiation oncology groups in the country and is co-director of the Gamma Knife Center at the University of Minnesota.  He created a prognostic index for brain tumor patients that has been widely adopted and developed a smart phone app to facilitate use by physicians.  He has been an advisor for several start-ups in health care technology and policy. 

Paul holds three Duke degrees (AB’80, MD’84, MPP’84) and did two years of internal medicine at Duke (HS’85-87) before going to the National Cancer Institute to finish his training in Radiation Oncology.  A partial list of other distinctions include: Society of Neuro-Oncology’s Award for Excellence in Clinical Research for work on a landmark clinical trial that changed the standard of care for patients with brain metastases (Lancet 2004); American Cancer Society’s Lane W. Adams Award for excellence in caring and promoting quality of life in cancer patients; one of 15 “future leaders of America” to receive the Henry Luce Scholarship for one year in Asia, for which he prepared by studying Mandarin at Middlebury College; Reviewer for the Pentagon’s Medical Free Electron Laser Program; Hubert H. Humphrey Fellowship; Duke Medical School’s Jones Guerrero Scholarship for Research; and he is routinely listed among “Top Doctors” in Minneapolis St. Paul magazine.  He studied the National Health Service in England, completed rural health care projects in Appalachia, cyclone-relief projects in India and malaria prevention projects in Zanzibar, Tanzania. He has lectured around the world and taught medicine at Hunan Medical College, Changsha, China under the auspices of the Yale-China Association.

Paul and his wife Jody have endowed two programs at Duke: one at the Sanford School to support a health policy faculty position and one at the medical school to provide medical student scholarships for field work in global health. Jody and Paul served as co-chairs for their recent 35th year undergraduate reunion. Paul served on the Sanford School Board of Visitors from 2011-15 and joined the Duke Medical School Board of Visitors in 2015.

Paul and Jody live in Wayzata, MN, and enjoy tennis and travel. Jody Laursen Sperduto, (PhD Clinical Psychologist, MEd Special Education), a former Duke cheerleader, is active in multiple civic organizations and is a guardian ad litem for children at risk. They have three children, Luke (Harvard ’11), Maria (Dartmouth ’14) and Will (Duke ’16).